B U P L E U R U M . 1 2

This formula was produced for the purpose of filling the broad need for bupleurum-based harmonising prescriptions derived from Minor Bupleurum Combination (Xiao Chaihu Tang). This 7-ingredient traditional formula, considered a representative of the harmonising group, has a number of potential modern uses. However, it has some tendency to cause adverse reactions among those who could otherwise benefit from it. These reactions are usually due to the desired "liver-dredging" function of the formula, which results in release of pent up liver qi. In persons with blood deficiency, the liver qi release is uncontrolled and can cause emotional distress, headaches, or other undesired results. Therefor, the basic formula (bupleurum, scute, pinellia, ginger, ginseng, jujube, licorice) is modified by adding tang kuei and peony to nourish the blood and by adding cinnamon twig to aid the recirculation of qi (it treats a condition sometimes called "flushing up of qi", which produces symptoms in the upper body: cinnamon twig aids the kidney in circulating the qi downward). A traditional modification of Minor Bupleurum Combination, Bupleurum and Cinnamon Combination (Chaihu Guizhi Tang), includes two of these additions - cinnamon and peony - and it alleviates the typical problem of flushing up.

Digestive disorders are common among persons with the disharmony syndrome. The traditionally used herb pair, hoelen is substituted her by fu-shen, which has the same property; it also has a calming quality, because it includes a protion of the sedative pine root that the mushroom grows around. The addition of atractylodes makes the formula similar to another widely used prescription, Bupleurum and Tang Kuei Formula (Xiao Yao San), which includes bupleurum, tang-kuei, peony, hoelen, atractylodes, ginger, and licorice that are also in Bupleurum 12.

Finally, to help regulate the central circulation of qi, chih-shih was added. This ingredient is a type of citrus that aids the downward circulation of qi. It helps clear the gallbladder and alleviates abdominal fullness. Chih-shih, along with three other ingredients of the Bupleurum 12 formula, bupleurum, peony and licorice, make up the traditional Bupleurum and Chih shih Formula (Sini San).

Jujube was left out because its contribution of tonifying and moistening was already accomplished. Qi tonification and improvement of stomach/spleen function is provided by ginseng, ginger, licorice, atractylodes, pinellia, and fu shen, and the drying quality of the qi dispersing and moisture resolving ingredients is ompenesated by the inclusion of tang kuei and peony.

The specific design is aimed at treating the most comon manifestations of the disorder - liver qi stagnation with liver blood deficiency and stomach/spleen weakness and distress - while minimising the chance of discomfor from releasing the pent up liver qi.

Ingredients
Available on request.

General activities
Mediate harmony, disperse qi and moisture.

Sample indications for use
Hypersensitivity, digestive disturbance, aching in the muscles, persistent low-grade infection, strees, anxiety, and neurosis.

To personalise, add the following formula
Fu Shen 16 or Ardisia 16 for agitation, insomnia, burning sensation, oral ulceration
Nuphar 14 for liver qi disorders with heat symptoms
Shen Chu 16 or Gallus Malt Tablets for food stagnation
Bupleurum S for epigastric pain, acid reflux, or abdominal bloating
Cyperus 18 for anxiety, stress reaction, and digestive disturbance
Tang Kuei 18 for abdominal pain, anemia
This formula may be used for acute disorders or on a regular basis for adjusting the constitution.

Manufacturing specifications
Crude herbs are powdered and formed into 700 mg tablets. Bottling of 100, 250 and 420 tablets.

Explanatory notes
Bupleurum 12 is the principal harmonising therapy provided in the Seven Forests tablets. It represents a merging of three ancient prescriptions that are widely used today: Bupleurum & Cinnamon Combination (Chaihu Guizhi Tang, a derivative Xiao Chaihu Tang), Bupleurum and Tang Kuei Formula (Xiaoyao San), and Bupleurum and Chih Shih Formula (Sini San). Fu shen replaces the related herb hoelen, while mentha and jujube are deleted (relative to these base formulas). This prescription can be used as the basis for any harmonising therapy, and it combines well with many other formulas, though the most common prescriptions to mix with it are those with overlapping activities: dispersing qi stagnation, improving the function of the stomach and spleen, resolving accumulation of moisture and phlegm, and alleviating stree. The general syndrome addressed by this formula is one in which the liver is functionally disturbed, causing agitation, stomach distress, and tension or congestion of the areas affected by the liver meridian. Cinnamon twig with peony opens the meridians; peony with licorice relaxes tension; bupleurum with chih shih disperses the congested liver qi and promotes gallbladder function; tang kuei with peony nourishes and relaxes the liver; ginseng with licorice invigorates the spleen and reinforces the stomach; pinellia with atractylodes improves stomach function and prevents accumulation of moisture and phlegm; scute with fu shen calms agitated spirit. The pairings of herbs in this formula are numerous and the resulting effects are easily applied with great versatility. See also: Remission Tablets.


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