G E N T I A N A . 1 2

General Activities
clear heat and dampness, purge fire

Sample Indications for Use
damp-heat syndromes, such as urogenital infections and chronic inflammation; liver fire syndromes, such as red eyes, headache, oral ulceration

To Personalise, Add
Plantago Seed Tablets for skin diseases of the legs and feet and for hemorrhoids
Isatis 6 or Paris 7 for herpes infection
Pyrossia 14 for urinary tract infection
Lindera 15 for prostate inflammation and pelvic inflammatory disease
Bupleurum 12 for active hepatitis
Myrrh Tablets or Red Peony Tablets for painful herpes zoster eruptions or other skin eruptions

This formula is intended only for short-term therapy, from 1-2 days for an infection or herpes eruption, to 3-4 weeks for treating chronic liver fire syndrome.

Manufacturing Specifications
Crude herbs are powdered and the mixture is formed into 700 mg tablets. Bottling of 100 or 250 tablets.

Explanatory Notes
Gentiana 12 is a derivative of the traditional formula Gentiana Combination (Longdan Xiegan Tang), which is the primary formula of Chinese medicine recommended for acute syndromes of liver fire and damp-heat. The basic formula has been modified here by using additional herbs to purge liver fire and clean toxins: coptis and sophora. Further, kadsura bark and moutan are included to promote circulation of blood. Liver fire may manifest symptoms of red eyes, facial flushing, swellings in the upper body, oral ulcerations, hyperactivity, and insomnia (see Fu Shen 16 for sedating liver yang agitation). Damp-heat usually manifests as moist sores, especially infections affecting the mucous membranes and the lower body. The toxin clearing and blood vitalising additions make the formula especially useful for infections and swellings. Gentiana is one of the stronger agents for purging liver fire and damp-heat, but it can also cause diarrhea if used over an extended period. Therefore, it is best to use the formula in full dosage for a brief time and then either reduce the dosage or switch to another prescription that has a milder action but can be taken for several months, if necessary (examples: Eclipta Tablets or Salvia-Ligustrum for hepatitis; Cnidium 9 for headache; Chien li Tablets for eye inflammation). In treating an infection outbreak, such as herpes simplex, or a skin infection (bacterial or fungal) it is best to take this formula at high dosage, up to 6 tablets each time, 3 times daily, for a few days.

Gentiana, Moutan, Plantago seed, Bupleurum, Sophora, Rehmannia, Tang Kuei, Scute, Gardenia, Coptis, Kdsurea Bark, Licorice
Pin Yin
longdancao, mudanpi, cheqianzi, chaihu, kushen, shengdi, danggui, huangqin, zhizi, huanglian, zijingpi, gancao